Background:
More than 340,000 persons in the Objective: Characterize dialysis event rates and vascular access use
among chronic hemodialysis patients Methods: Dialysis event surveillance data reported to NHSN from
outpatient facilities during 2007-2008 were analyzed. Numerator data are based
on event reports made for patients who had a positive blood culture (i.e.,
BSI), received outpatient intravenous (IV) antibiotics, or had an overnight
hospitalization for any cause. The reported number of patients treated in a
facility on the first 2 days of the month (monthly patient census) was used as
the denominator and the vascular access distribution of these patients was
determined. Pooled mean rates and 95% confidence intervals were stratified by vascular
access type and calculated per 100 patient-months. Medians were compared using
the Wilcoxon rank sum test. Results: A total of 49 outpatient dialysis facilities reported 10,193
events among 66,694 patient-months during 2007-2008. Twenty-six (53%)
facilities were based in, or affiliated with an acute-care hospital; the median
average monthly census was 54 (range 15 - 348). The pooled mean rates of BSI,
IV antibiotic starts, and hospitalizations were highest among patients with CVCs and lowest for those with fistulas (Table). Median
facility vascular access use was 48.1% for fistulas and 34.8% for permanent CVCs, with substantial inter-facility variation. Although
duration of CVC use could not be determined, all facilities had > 10%
average prevalence of permanent CVCs. Compared to
other facilities, hospital-affiliated outpatient facilities had lower median
fistula use (45.9% vs. 51.7%; p=0.10) and higher permanent CVC use (37.7% vs.
27.7%; p=0.02). Vancomycin was used in 75.9% of 2989
IV antibiotic starts reported. Of 1593 BSIs reported,
70.4% occurred among patients with a CVC. Conclusions: Rates of adverse events continue to be highest among
dialysis patients with CVCs, and these patients
contributed most to the overall burden of BSIs.
Dedicated efforts are needed, in both hospital-based and other dialysis
facilities, to reduce catheter use and prevent infections among hemodialysis patients who are catheter-dependent.