Objective: To compare CDI related hospitalizations to MRSA related hospitalizations from National Healthcare Cost and Utilization Project (HCPUP) data in 2007.
Methods: Data from the 2007 HCPUP, Nationwide Inpatient Sample (NIS) were analyzed to identify CDI-associated hospitalizations. All hospitalizations with a diagnosis of CDI (ICD-9 code 8.45) were defined as CDI-associated hospitalizations. The HCUP-NIS data represents a stratified sample of approximately 20% of non-federal community hospitals in the US and were weighted for national projections. We utilized HCUP data to calculate national estimates of CDI and MRSA related hospitalizations in the year 2007.
Results: Of the total 39.5 million hospitalizations in the year 2007, 325,022 cases of CDI and 420,153 MRSA-associated hospitalizations were seen. This translates into 0.8% and 1.1% of hospitalizations respectively. The CDI related hospitalizations in 2007 increased to 325,022 cases as compared to 291,303 cases of CDI related hospitalizations in the year 2005, an increase of 11.6 % in 2 years.
Conclusions: With this concerning rise in national CDI related hospitalizations and in the face of aging population ,there is a critical need for strong antibiotic stewardship programs in the country to face this growing challenge.